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FOSAMAX (alendronate)

Osteoporosis is a preventable condition that all women (and men) need to be concerned about. Osteoporosis is the rapid thinning of bones after menopause that leaves them fragile and susceptible to fractures. Fortunately, current treatment strategies offer hope by reducing risk factors for osteoporosis and if one already has it, you can live with it comfortably and safely.

Fosamax is indicated for the prevention and treatment of osteoporosis and was approved by the FDA on April 1997. Fosamax is a bisphosphonate which inhibits bone breakdown by inhibiting osteoclast activity (cells that break down bone). Numerous studies have shown the effectiveness of this treatment in reducing both spinal (47%) and hip fractures (51%). Recent studies have shown that beneficial effects occur as early as 3 months. Fosamax is only part of the overall treatment management for osteoporosis. Please consult your physician for individualized treatment strategies.

  • 5 or 10mg daily
  • Must be taken at least ½ hour before food, beverage or medication (including calcium and Vitamin D) with 8oz of water first after arising in the morning; do not lie down for at least 30 minutes.
Drug Interactions:

No drug interactions were noted in clinical trials. However, patients taking aspirin products have reported increased gastrointestinal symptoms. Not recommended in people with severe renal insufficiency (creatine clearance <35ml/min).

Adverse Effects: Please note most individuals will not have any side effects!

  • Abdominal pain   6. 6%
  • Nausea               3. 6%
  • Dyspepsia           3. 6%
  • Constipation       3. 1%
  • Diarrhea             3. 1%
  • Esophageal ulcer  1. 5%
  • Gastritis              . 5%
  • Head Aches:       2. 6%
  • Muscle pain:      4. 1%

Pregnancy category C: No adequate studies have been done. Should only be used if the potential benefit justifies the potential risk to the mother and fetus. Should not be used in Nursing women.

Children: Pediatric safety has not been established.

If you have any further questions or concerns please consult your physician. If you develop any side effects please stop the medication and contact your physician.

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Chesterfield, MO 63017
Telephone: 314-469-PAIN (7246)

Fax: 314-469-7251
Exchange: 314-441-6965 (for after-hour Emergencies Only)

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